Just before Killer Mike helped him realize his dream of starting a cyberpunk EPMD, El-P was the kind of uncompromising solo artist that made his Run the Jewels popularity all the more remarkable. While he kept both feet in hip-hop roots, he found power in a tendency to create beats that made synthesizers sound unbearably filthy before turning his run-on flow against their very structure. And after the 2008 death of his close friend Camu Tao and the 2010 conclusion of his Definitive Jux label, Cancer4Cure sounds like El turning his catharsis into a call for solidarity, whether it’s with victims of personal and systematic abuse, or against the plague of fuck shit that fuels it.